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1

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

Kristensen, A. S., Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pohlsgaard, J., Clausen, R. P., Gajhede, M., Kastrup, J. S., Traynelis, S. F.

Journal:

Molecular Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2016

2

Structure analysis of modulated molecular crystals: The modulated phase of thiourea as described by a molecular displacement model

Gao, Y., Gajhede, M., Mallinson, P., Petricek, V., Coppens, P.

Journal:

Physical Review B

Année:

1988

Langue:

english

Fichier:

PDF, 871 KB

english, 1988

3

The tunnel effect and scattering by a negative Kratzer potential

C.J. Ballhausen, Michael Gajhede

Journal:

Chemical Physics Letters

Année:

1990

Langue:

english

Fichier:

PDF, 244 KB

english, 1990

4

The Structures of the Horseradish Peroxidase C-Ferulic Acid Complex and the Ternary Complex with Cyanide Suggest How Peroxidases Oxidize Small Phenolic Substrates

Henriksen, A., Smith, A. T., Gajhede, M.

Journal:

Journal of Biological Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1999

5

Recurrence of Achilles tendon injuries in elite male football players is more common after early return to play: an 11-year follow-up of the UEFA Champions League injury study

Gajhede-Knudsen, M., Ekstrand, J., Magnusson, H., Maffulli, N.

Journal:

British Journal of Sports Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 439 KB

english, 2013

6

Plant peroxidases: substrate complexes with mechanistic implications

Journal:

Biochemical Society Transactions

Année:

2001

Langue:

english

Fichier:

PDF, 823 KB

english, 2001

7

The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

AmbjÃ¸rner, Sophie E. B., Wiese, Michael, KÃ¶hler, Sebastian Christoph, Svindt, Joen, Lund, Xamuel Loft, Gajhede, Michael, Saaby, Lasse, Brodin, Birger, Rump, Steffen, Weigt, Henning, BrÃ¼nner, Nils,

Journal:

Année:

2020

Fichier:

PDF, 2.54 MB

2020

8

Crystallization and preliminary x-ray investigation at 2.0 Å resolution of Bet v 1, a birch pollen protein causing IgE-mediated allergy

Spangfort, Michael D., Larsen, Jørgen N., Gajhede, Michael

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1996

Langue:

english

Fichier:

PDF, 318 KB

english, 1996

9

Targeting Histone Lysine Demethylases by Truncating the Histone 3 Tail to Obtain Selective Substrate-Based Inhibitors

Brian Lohse, Anders L. Nielsen, Jan B. L. Kristensen, Charlotte Helgstrand, Paul A. C. Cloos, Lars Olsen, Michael Gajhede, Rasmus P. Clausen, Jesper L. Kristensen

Journal:

Angewandte Chemie

Année:

2011

Langue:

english

Fichier:

PDF, 342 KB

english, 2011

10

Targeting Histone Lysine Demethylases by Truncating the Histone 3 Tail to Obtain Selective Substrate-Based Inhibitors

Brian Lohse, Anders L. Nielsen, Jan B. L. Kristensen, Charlotte Helgstrand, Paul A. C. Cloos, Lars Olsen, Michael Gajhede, Rasmus P. Clausen, Jesper L. Kristensen

Journal:

Angewandte Chemie International Edition

Année:

2011

Langue:

english

Fichier:

PDF, 325 KB

english, 2011

11

ChemInform Abstract: Cyclic Lipoundecapeptide Tensin from Pseudomonas fluorescens Strain 96.578.

Anette Henriksen, Uffe Anthoni, Tommy H. Nielsen, Jan Soerensen, Carsten Christophersen, Michael Gajhede

Journal:

Année:

2000

Fichier:

PDF, 28 KB

2000

12

ChemInform Abstract: Cyclic Lipoundecapeptide Amphisin from Pseudomonas sp. Strain DSS73.

Dan Soerensen, Tommy H. Nielsen, Carsten Christophersen, Jan Soerensen, Michael Gajhede

Journal:

Année:

2002

Fichier:

PDF, 24 KB

2002

13

Cyclic Acetals. Structural Analysis of 1,3-Dioxepine and Related Compounds

Flemming S. Jørgensen, Michael Gajhede, Bruno Frei

Journal:

Helvetica Chimica Acta

Année:

1985

Langue:

english

Fichier:

PDF, 532 KB

english, 1985

14

Ab initio electric field gradient calculations for a series of oxygen-containing boron compounds

Michael Gajhede

Journal:

Chemical Physics Letters

Année:

1985

Langue:

english

Fichier:

PDF, 392 KB

english, 1985

15

Hydrogen bonding in 3-azetidinol: Part 2. On the presence of inter- and intra-molecular interactions in solution and in the gas phase

Uffe Anthoni, Daniel Højgaard Christensen, Carsten Christophersen, Michael Gajhede, Lars Henriksen, Ole Faurskov Nielsen, Per Halfdan Nielsen

Journal:

Journal of Molecular Structure

Année:

1990

Langue:

english

Fichier:

PDF, 783 KB

english, 1990

16

Hydrogen bonding in 3-azetidinol—3. Ab initio and experimental spectra of the hydrogen-bonded species

Uffe Anthoni, Carsten Christophersen, Per Halfdan Nielsen, Daniel Højgaard Christensen, Ole Faurskov Nielsen, Michael Gajhede

Journal:

Spectrochimica Acta Part A: Molecular Spectroscopy

Année:

1989

Langue:

english

Fichier:

PDF, 700 KB

english, 1989

17

Inhibitors of histone demethylases

Brian Lohse, Jesper L. Kristensen, Line H. Kristensen, Karl Agger, Kristian Helin, Michael Gajhede, Rasmus P. Clausen

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2011

18

Structural Proof of a Dimeric Positive Modulator Bridging Two Identical AMPA Receptor-Binding Sites

Birgitte H. Kaae, Kasper Harpsøe, Jette S. Kastrup, Alberto Contreras Sanz, Darryl S. Pickering, Bjørn Metzler, Rasmus P. Clausen, Michael Gajhede, Per Sauerberg, Tommy Liljefors, Ulf Madsen

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 693 KB

english, 2007

19

Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple

J. Holm, G. Bærentzen, M. Gajhede, H. Ipsen, J.N. Larsen, H. Løwenstein, M. Wissenbach, M.D. Spangfort

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

2001

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2001

20

Reassignment of the fundamental vibrations of azetidine from ab initio calculations

Per Halfdan Nielsen, Michael Gajhede

Journal:

Journal of Physical Organic Chemistry

Année:

1989

Langue:

english

Fichier:

PDF, 228 KB

english, 1989

21

Major venom allergen of yellow jackets, Ves v 5: Structural characterization of a pathogenesis-related protein superfamily

Anette Henriksen, Te P. King, Osman Mirza, Rafaél I. Monsalve, Kåre Meno, Henrik Ipsen, Jørgen N. Larsen, Michael Gajhede, Michael D. Spangfort

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2001

Langue:

english

Fichier:

PDF, 504 KB

english, 2001

22

Towards the molecular understanding of glycogen elongation by amylosucrase

Cécile Albenne, Lars K. Skov, Vinh Tran, Michael Gajhede, Pierre Monsan, Magali Remaud-Siméon, Gwénaëlle André-Leroux

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2007

Langue:

english

Fichier:

PDF, 482 KB

english, 2007

23

Pancreatic spasmolytic polypeptide: Crystallization, circular dichroism analysis, and preliminary X-ray diffraction studies

Dr. Michael Gajhede, Lars Thim, Klavs H. Jørgensen, Steen G. Melberg

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1992

Langue:

english

Fichier:

PDF, 488 KB

english, 1992

24

Modeling chemoadaptive behavior: X-ray structure of the trimethylamine oxide-urea (1∶4) complex

Uffe Anthoni, Carsten Christophersen, Michael Gajhede, Per H. Nielsen

Journal:

Structural Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 751 KB

english, 1992

25

Carnosol. Crystal structure, absolute configuration, and spectroscopic properties of a diterpene

Michael Gajhede, Uffe Anthoni, Halfdan Per Nielsen, Erik Jonas Pedersen, Carsten Christophersen

Journal:

Journal of Chemical Crystallography

Année:

1990

Langue:

english

Fichier:

PDF, 579 KB

english, 1990

26

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP

Bettina B. Nielsen, Darryl S. Pickering, Jeremy R. Greenwood, Lotte Brehm, Michael Gajhede, Arne Schousboe, Jette S Kastrup

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 429 KB

english, 2005

27

Increased amylosucrase activity and specificity, and identification of regions important for activity, specificity and stability through molecular evolution

Bart A. van der Veen, Lars K. Skov, Gabrielle Potocki-Véronèse, Michael Gajhede, Pierre Monsan, Magali Remaud-Simeon

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 385 KB

english, 2006

28

X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy

Gajhede, Michael, Osmark, Peter, Poulsen, Flemming M., Ipsen, Henrik, Larsen, Jørgen N., van Neerven, R.J. Joost, Schou, Carsten, Løwenstein, Henning, Spangfort, Michael D.

Journal:

Natural Structural Biology

Année:

1996

Fichier:

PDF, 857 KB

1996

29

Crystal structure of horseradish peroxidase C at 2.15 Å resolution

Gajhede, Michael, Schuller, David J., Henriksen, Anette, Smith, Andrew T., Poulos, Thomas L.

Journal:

Natural Structural Biology

Année:

1997

Fichier:

PDF, 1.25 MB

1997

30

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

Lars Østergaard, Kaare Teilum, Osman Mirza, Ole Mattsson, Morten Petersen, Karen G. Welinder, John Mundy, Michael Gajhede, Anette Henriksen

Journal:

Plant Molecular Biology

Année:

2000

Langue:

english

Fichier:

PDF, 195 KB

english, 2000

31

Pancreatic spasmolytic polypeptide: first three-dimensional structure of a member of the mammalian trefoil family of peptides

M Gajhede, TN Petersen, A Henriksen, JFW Petersen, Z Dauter, KS Wilson, L Thim

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 11.74 MB

english, 1993

32

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

Christina Kasper, Karla Frydenvang, Peter Naur, Michael Gajhede, Darryl S. Pickering, Jette Sandholm Kastrup

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 976 KB

english, 2008

33

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

Jan B.L. Kristensen, Anders L. Nielsen, Lars Jørgensen, Line H. Kristensen, Charlotte Helgstrand, Lina Juknaite, Jesper L. Kristensen, Jette S. Kastrup, Rasmus P. Clausen, Lars Olsen, Michael Gajhede

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 684 KB

english, 2011

34

Erratum to “Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases” [FEBS Lett. 585 (2011) 1951–1956]

Jan B.L. Kristensen, Anders L. Nielsen, Lars Jørgensen, Line H. Kristensen, Charlotte Helgstrand, Lina Juknaite, Jesper L. Kristensen, Jette S. Kastrup, Rasmus P. Clausen, Lars Olsen, Michael Gajhede

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 167 KB

english, 2011

35

Identification of catechols as histone–lysine demethylase inhibitors

Anders L. Nielsen, Line H. Kristensen, Karen B. Stephansen, Jan B.L. Kristensen, Charlotte Helgstrand, Michael Lees, Paul Cloos, Kristian Helin, Michael Gajhede, Lars Olsen

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 561 KB

english, 2012

36

Chaperone Binding at the Ribosomal Exit Tunnel

Ole Kristensen, Michael Gajhede

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 535 KB

english, 2003

37

Structural Model and trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule

Nikolaj Kulahin, Ole Kristensen, Kim K. Rasmussen, Lars Olsen, Patrik Rydberg, Bente Vestergaard, Jette S. Kastrup, Vladimir Berezin, Elisabeth Bock, Peter S. Walmod, Michael Gajhede

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 848 KB

english, 2011

38

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

Line H. Kristensen, Anders L. Nielsen, Charlotte Helgstrand, Michael Lees, Paul Cloos, Jette S. Kastrup, Kristian Helin, Lars Olsen, Michael Gajhede

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2012

39

A Tetrazolyl-Substituted Subtype-Selective AMPA Receptor Agonist⊥

Vogensen, Stine B., Frydenvang, Karla, Greenwood, Jeremy R., Postorino, Giovanna, Nielsen, Birgitte, Pickering, Darryl S., Ebert, Bjarke, Bølcho, Ulrik, Egebjerg, Jan, Gajhede, Michael

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 394 KB

english, 2007

40

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

Rohde, L. A. H., Ahring, P. K., Jensen, M. L., Nielsen, E. O., Peters, D., Helgstrand, C., Krintel, C., Harpsoe, K., Gajhede, M., Kastrup, J. S.

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2012

41

Crystallization and Preliminary X-ray Diffraction Studies on the Apo form of Orotate Phosphoribosyltransferase from Escherichia coli

Nushin Aghajari, Kaj Frank Jensen, Michael Gajhede

Journal:

Journal of Molecular Biology

Année:

1994

Fichier:

PDF, 176 KB

1994

42

Crystallization and preliminary X-ray diffraction studies of a peroxidase from barley grain

Anette Henriksen, Jens F.W. Petersen, Anders Svensson, Jørn Hejgaard, Karen G. Welinder, Michael Gajhede

Journal:

Journal of Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1992

43

High resolution crystal structures of the p120 RasGAP SH3 domain

Birthe Ross, Ole Kristensen, Dimitri Favre, Joël Walicki, Jette S. Kastrup, Christian Widmann, Michael Gajhede

Journal:

Biochemical and Biophysical Research Communications

Année:

2007

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2007

44

Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross-reactivity

Birthe R. Johannessen, Lars K. Skov, Jette S. Kastrup, Ole Kristensen, Caroline Bolwig, Jørgen N. Larsen, Michael Spangfort, Kaare Lund, Michael Gajhede

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 399 KB

english, 2005

45

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

Peter Naur, Bente Vestergaard, Lars K. Skov, Jan Egebjerg, Michael Gajhede, Jette Sandholm Kastrup

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 412 KB

english, 2005

46

The Structure of a Mixed GluR2 Ligand-binding Core Dimer in Complex with (S)-Glutamate and the Antagonist (S)-NS1209

Christina Kasper, Darryl S. Pickering, Osman Mirza, Lars Olsen, Anders S. Kristensen, Jeremy R. Greenwood, Tommy Liljefors, Arne Schousboe, Frank Wätjen, Michael Gajhede, Bent W. Sigurskjold, Jette S.

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 899 KB

english, 2006

47

Structure of the PPX/GPPA Phosphatase from Aquifex aeolicus in Complex with the Alarmone ppGpp

Ole Kristensen, Birthe Ross, Michael Gajhede

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2008

48

Crystal Structure of the Ig1 Domain of the Neural Cell Adhesion Molecule NCAM2 Displays Domain Swapping

Kim K. Rasmussen, Nikolaj Kulahin, Ole Kristensen, Jens-Christian N. Poulsen, Bent W. Sigurskjold, Jette S. Kastrup, Vladimir Berezin, Elisabeth Bock, Peter S. Walmod, Michael Gajhede

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1012 KB

english, 2008

49

Distinct Structural Features of Cyclothiazide Are Responsible for Effects on Peak Current Amplitude and Desensitization Kinetics at iGluR2

Helle Hald, Philip K. Ahring, Daniel B. Timmermann, Tommy Liljefors, Michael Gajhede, Jette S. Kastrup

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2009

50

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

Raminta Venskutonytė, Karla Frydenvang, Michael Gajhede, Lennart Bunch, Darryl S. Pickering, Jette S. Kastrup

Journal:

Journal of Structural Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2011